Blanch the bones. This step is SO IMPORTANT. If you want a clear, beautiful pho broth, blanch your bones. Do this by dividing the bones between two large pots or stockpots. Cover with cold water. Bring to a boil over high heat and simmer for 15-20 minutes. Drain and rinse the bones with water.
Roast the bones and the vegetables (optional). Preheat the oven to 450 degrees F. Transfer the bones, onion, garlic, and ginger to the roasting pans or rimmed baking sheets (you'll probably need two). Don’t pile them all on top of each other. Roast for 30 minutes before gently tossing the bones, and roasting for an additional 15-30 minutes more (for a total of 45-60 minutes).
Toast the spices. As the bones are roasting, add all of your spices (the star anise, cinnamon, cloves, cardamom pods, coriander seeds, and fennel seeds) to a large, dry skillet over low heat. Toast the spices, stirring often to prevent burning, until fragrant, approximately 5 minutes. Divide the spices in half. Cut cheesecloth into two small square pieces (approximately 5-inches by 5-inches) each. Transfer the divided spices to the center of each square. Gather at the top and secure with kitchen twine. Transfer the roasted bones and veggies back to the stockpots. Making sure to wash the pots after the bones were blanched and drained. Transfer and divide the roasted bones, onion, garlic, and ginger back to the stockpots. Scrape up any remaining bits and juices left in the roasting pan using a metal spatula and a little water, if needed. Add to the pot with the bones (don’t worry, all those brown bits are FLAVOR!).
Bring to a boil. With the bones, spice sachets (one per pot), onion, garlic, and ginger divided between the two pots, fill each pot with approximately 12 cups water (or until bones are fully submerged), 1/3 cup fish sauce and 2 tablespoons of sugar. Bring to a boil.
Simmer the bones. Immediately reduce heat to low and simmer, with the lid slightly ajar, skimming any foam or excess fat, occasionally (if you blanched your bones, you shouldn’t see much foam). Simmer for at least 6-12 hours, ideally 24 hours (do not leave the stove running overnight. Simply cool and store in the refrigerator and continue to simmer the next day). Add more water if needed to make sure the bones stay submerged.
Strain the broth. Once the bones have simmered and your hot broth is ready, strain it through a fine-mesh strainer or colander into a clean pot. This separates the pretty, clear broth from the bones and spices.
Season to taste. Add additional salt (you'll probably need a little), soy sauce, fish sauce, sugar or rock sugar (found at Asian markets), to taste. Set aside the broth to cool (if you're not using right away) and reserve the bones.
Don’t forget about the meat. I can almost guarantee that there is a TON of delicious meat waiting to be picked from the bones. Don’t let it go to waste! Discard the meat-free bones, herbs, and other bits that were used to make the broth, but save the meat and add to sandwiches, wraps, salads, or back to your broth.
Skim the fat from the top (optional). Add a couple of handfuls of ice to your broth to expedite cooling and cover your pot with a lid. Transfer the broth to the refrigerator and allow the broth to cool fully (this will take upwards of 6 hours or overnight). The result will be a hard, thick layer of fat on the top and a bottom layer that is your pho broth (which should look like gelatinous brown jello). If desired use a fork to scoop off the top layer of fat.